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KMID : 1094719960010010036
Biotechnology and Bioprocess Engineering
1996 Volume.1 No. 1 p.36 ~ p.40
Production ofcis,cis-muconic acid from benzoic acidvia microbial transformation
Bang Sang-Gu

Choi Won-Jae
Choi Cha-Yong
Cho Moo-Hwan
Abstract
For the production ofcis,cis-muconic acidvia biocatalytic conversion reactions from a toxic cosubstrate, benzoic acid, a fed-batch process using computer-controlled DO-stat feeding was developed. The mutant strain ofPseudomonas putida BM014 producedcis,cis-muconic acid from benzoic acid with high conversion yield. More than 32 g/L ofcis,cis-muconic acid was accumulated in 42h and a productivity of 1.4 g/(L¡¤h) was achieved.
KEYWORD
cis,cis-muconic acid, fed-batch process, Pseudomonas putida
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